By F. Bachmann, Prof. Fedor Bachmann (auth.), Dr. N. Friedel, Prof. Dr. R. Hetzer, Dr. D. Royston (eds.)

ISBN-10: 3662061198

ISBN-13: 9783662061190

ISBN-10: 366206121X

ISBN-13: 9783662061213

Cardiac surgical procedure has constructed dramatically because the first open-he paintings operations have been played within the mid Nineteen Fifties. even though the development of surgical strategy, extracorporeal circulate, and postoperative administration has contributed to a marked relief of morbidity and mortality, the advance of cardiac surgical procedure to its current nation do not have been attainable with no blood substitution by means of homologous donor blood. simply two decades in the past, open-heart operations required a typical of eight devices of blood preserves. The over the top desire of donor blood in these early days was once quite often because of untimely surgical strategy, insecure keep an eye on of anticoagulation, serious blood trauma via extracorporeal stream, and the inability of retransfusion applied sciences that might have allowed the reuse of shed mediastinal blood. The creation of latest applied sciences, resembling normovolemic hemodilution, in­ traoperative autotransfusion, postoperative go back of shed mediastinal blood, and predonation of autologous blood has vastly lowered donor blood requisites. at this time nearly all of regimen coronary artery surgeries may be played with none blood transfusion. Blood loss, despite the fact that, should be huge in sufferers present process advanced valve surgical procedure or reoperations, as they generally require numerous devices of transfused blood. Blood conservation has now turn into a space of significant curiosity for the cardiac general practitioner. This elevated situation is brought on by infectious issues of blood transfusion, specifically hepatitis and, extra lately, AIDS.

Show description

Read or Download Blood Use in Cardiac Surgery PDF

Best surgery books

Read e-book online Laparoscopic Surgery of the Abdomen PDF

An in-depth research of the technical elements of the main typically played laparoscopic tactics, their symptoms, contraindications, and issues. seriously illustrated, Laparoscopic surgical procedure of the stomach breaks new floor in visualising operative tactics and difficulties. Seven sections, comprising the middle curriculum of permitted approaches, current gallbladder illness, universal bile duct exploration, hernia, colon illnesses, anti-reflux strategies, acute stomach and the position of diagnostic laparoscopy, and rising systems at the spleen and adrenals.

Read e-book online Pediatric Fractures and Dislocations PDF

This crucial new textual content assesses the advantages of conservative as opposed to surgical operation of pediatric fractures, combining transparent procedural instructions with an research of the best operative process. greater than 500 pages supply exact, complete insurance of ideas and techniques, with 450 illustrations clarifying all techniques.

Lewis Spitz, Arnold Coran's Operative Pediatric Surgery PDF

The 6th version of this acclaimed operative atlas maintains to supply a different point of entire element at the complete diversity of stipulations offered in adolescence, together with the fetus and neonate, that may be handled through surgical capacity. All chapters were completely revised and up-to-date all through with new line diagrams the place beneficial.

Cardio-aortic and Aortic Surgery - download pdf or read online

As societies have elderly and aortic ailments became extra established, advances in diagnostic imaging and surgical suggestions have introduced considerably better effects for sufferers. In cardiovascular surgical procedure, very important questions stay to be addressed, even if. "Strategy for Cardio-aortic and Aortic surgical procedure" used to be the topic of the seventh Keio college foreign Symposium for all times Sciences and medication.

Extra resources for Blood Use in Cardiac Surgery

Sample text

Blood 65 32-40 72. Adelman B, Michelson AD, Greenberg J and Handin RI (1986) Proteolysis ofplatelet glycoprotein Ib by plasmin is facilitated by plasmin lysine-binding regions. Blood 68: 1280-1284 25 73. Stricker RB, Wong D, Shiu DT, Reyes PT and Shuman MA (1986) Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: Effects on surface proteins and platelet aggregation. Blood 68: 275-280 74. Takamatsu J, Horne MK and Gralnick HK (1986) Identification of the thrombin receptor on human platelets by chemical crosslinking.

J Bio!. Chem 260: 11107-11114 7. Leung LLK (1984) Role ofthrombospondin in platelet aggregation. J. Clin Invest 74: 17641772 8. Hsu-Lin S-c. Berman CL, Furie BC, August D and Furie B (1984) A platelet membrane protein expressed during platelet activation and secretion. Studies using a monoclonal antibody specific for thrombin-activated platelets. J Bio!. Chem 259: 9121-9126 9. Stenberg PE, McEver RP, Shuman MA, Jacques YV and Bainton DF (1985) A platelet alphagranule membrane protein (GMP-140) is expressed on the plasma membrane after activation.

Surface-bound XIIa cleaves bound prekallikrein to kallikrein, and Factor XI to XIa. Factor XIa is tightly bound to activated HK and slowly dissociates to catalyze Factor IX to IXa [87]. Kallikrein readily dissociates from the surface [87] to accelerate and amplify the contact pathway. Kallikrein reciprocally activates Factor XII, but also cleaves and activates HK, plasminogen [22], prorenin, Cl [26], and it stimulates neutrophils [24, 94]. Activation of the contact system initiates coagulation, activates neutrophils, and pro duces kallikrein, bradykinin, renin and plasmin [25].

Download PDF sample

Blood Use in Cardiac Surgery by F. Bachmann, Prof. Fedor Bachmann (auth.), Dr. N. Friedel, Prof. Dr. R. Hetzer, Dr. D. Royston (eds.)


by Paul
4.1

Rated 4.45 of 5 – based on 3 votes