By Lodovico Balducci (Editor), Martine Extermann (Editor)

ISBN-10: 0387239618

ISBN-13: 9780387239613

ISBN-10: 0387239626

ISBN-13: 9780387239620

Organic foundation of Geriatric Oncology highlights examine matters which are particular to geriatric oncology within the box of carcinogenesis and melanoma prevention and remedy, in response to the biologic interactions of melanoma and age. It illustrates the advantage of the rules of geriatrics within the administration of melanoma within the older person. This quantity offers a body of reference for practicioners of any specialties enthusiastic about the administration of older sufferers and for oncologists enthusiastic about the administration of melanoma of older participants. it's a resource for easy and medical scientists exploring the interactions and rising info of melanoma and getting older.

Show description

Read or Download Biological Basis of Geriatric Oncology (Cancer Treatment and Research) PDF

Similar oncology books

Prostate and Cancer: A Family Guide to Diagnosis, Treatment, by Sheldon Marks MD PDF

Prostate melanoma is without doubt one of the commonest cancers affecting American males, with over 186,000 new situations clinically determined within the usa every year; 1 in 6 males can be clinically determined with prostate melanoma in the course of his lifetime. popular prostate melanoma expert Sheldon Marks deals the definitive advisor for males taken with or clinically determined with prostate melanoma, and for his or her households.

Ensuring Quality Cancer Care Through the Oncology Workforce: by Margie Patlak, Laura Levit PDF

The yankee Society of scientific Oncology (ASCO) predicts that by way of 2020, there'll be an eighty one percentage bring up in humans residing with or surviving melanoma, yet just a 14 percentage raise within the variety of practising oncologists. therefore, there is too few oncologists to fulfill the population's desire for melanoma care.

Luigi Grassi, Michelle Riba's Clinical Psycho-Oncology: An International Perspective PDF

This overseas primer on psycho-oncology spans settings of care in addition to local barriers. Designed to be effortless to learn, with informaton basically displayed in concise tables and packing containers followed through medical vignettes, the booklet provides clear, functional counsel on all features of the mental care of sufferers with melanoma.

Get Targeted Therapy in Translational Cancer Research PDF

Distinct remedy in Translational melanoma study for the Translational Oncology sequence presents a entire evaluate of contemporary advancements in our realizing of tumor biology, elucidates the jobs of objectives and pathways thinking about carcinogenesis, and describes present state of the art anticancer treatment, in addition to the main promising parts of translational examine and unique treatment.

Additional resources for Biological Basis of Geriatric Oncology (Cancer Treatment and Research)

Sample text

These mice and embryonal fibroblasts derived from them were more resistant to oxidative stress than controls. The spontaneous tumor incidence in the aging cohort of mice was similar to that in wild-type controls. At the molecular level, insulin receptor substrate and the p52 and p66 isoforms of Shc, both main substrates of IGF-1 receptor, showed decreased tyrosine phosphorylation. mediated cellular responses to oxidative stress. Two main pathways the extracellular-signal related kinase (ERK)/mitogen-activated protein kinase (MAPK) pathway and the phosphatidylinositol 3-kinase (PI3K)-Akt pathway – were downregulated in mice.

Mechanisms and Etiology of Tumor Promotion. IARC Scientific Publication No. 56. IARC. Lyon, France. 1984; 497-506 Hanahan D; Weinberg RA: The hallmarks of cancer. Cell 2000;100:57-70 Kaldor JM; Day NE: Interpretation of epidemiological studies in the context of the multistage model of carcinogenesis. ): Mechanisms of Environmental carcinogenesis. Boca Raton. FL. CRC Press. 1987; 2:21-57 Anisimov VN; Zhukovskaya NV; Loktionov AS; et al: Influence of host age on lung colony forming capacity of injected rat rhabdomyosarcoma cells.

The character of these changes could vary in different tissues and might cause uneven tissue aging. Dolle et al. 88 using a lacZ plasmid transgenic mouse model, determined spectra of spontaneous point mutations in different organs in young and old mice. While similar at a young age, the mutation spectra among these organs were significantly different in old age. The authors stressed that the replicative history per se is not the underlying causal factor of age-related organ-specific differences in mutations spectra.

Download PDF sample

Biological Basis of Geriatric Oncology (Cancer Treatment and Research) by Lodovico Balducci (Editor), Martine Extermann (Editor)

by Joseph

Rated 4.03 of 5 – based on 24 votes