By John Barrett (auth.)

ISBN-10: 0333256697

ISBN-13: 9780333256695

ISBN-10: 1349861197

ISBN-13: 9781349861194

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Verticil/a tum and in the nematodes A. lumbricoides, A. columnaris and A. galli. In A. lumbricoides, the wax esters are extremely unusual in that they consist of a long chain alcohol esterified, not with a long chain acid, but with a short chain volatile fatty acid I6 . The alcohol fraction of A. lumbricoides wax esters is mostly CIS, with small amounts of C I6 , C I7 and C19 • The acid component is largely 2-methylbutyrate with small amounts LIPIDS 35 of acetate, propionate and n-valerate and traces of n-butyrate and 2-methylvalerate.

Lumbricoides, for example, the ovarian triacylglycerols have a different fatty acid composition to the body-wall triacylglycerols. Whilst in H. diminuta, the fatty acid composition of polar lipids from isolated tegumental components (brush borders and vesicles) differs considerably from that of polar lipids prepared from whole worms 11 • In general, a similar range of fatty acids is found in free-living organisms and parasitic helminths, and the major fatty acids in both are usually C16 and C18.

Diminuta contains glucose. In mammals, galactose cerebrosides are characteristic of nervous tissue, glucose cerebrosides of non-nervous tissue. Cerebrosides have also been identified in the lipids of F hepatica, P. microbothrium, A. caninum and in the eggs, but not the adults, of S. mansoni. Cerebrosides were also not detected in larval T. spiralis. Characteristically, cerebrosides contain long chain, saturated and mono-unsaturated fatty acids, and in mammals hydroxy acids are common. The cerebrosides of H.

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Biochemistry of Parasitic Helminths by John Barrett (auth.)

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