By Jan H. Wong MD (auth.), Stanley P. L. Leong (eds.)
Atlas of Selective Lymphadenectomy for cancer, Breast melanoma and Colon Cancer emphasizes a multidisciplinary strategy combining the stories of a nuclear medication doctor, physician, and pathologist. this can be a tremendous reference additionally for researchers and clinicians who are looking to familiarize yourself with sentinel lymph node mapping. The underlying thesis in good tumor biology is that metastasis quite often starts off in an orderly development with lymphatic unfold first to the sentinel lymph node (SLN) within the nearest lymph node basin. for that reason, the logical technique is to reap that express SLN for thorough analysis.
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Extra info for Atlas of Selective Sentinel Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer
A general area can be marked as to the location of SLN and the surgeon advised. Intradermal injection A dynamic set is obtained as described. The injection of the tracer is placed above the tumor mass or mammographic finding. The gauze-covered injection site can be covered with a small piece of lead. This reduces the activity in the imaged area and 30 Atlas of Selective Sentinel Lymphadenectomy reduces the “shine effect” of the injection site. The lead does not impede the passage of tracer through the lymphatic channels.
Because of discordance between clinical predictions and lymphatic drainage as determined by preoperative lymphoscintigraphy [Leong 1999a] preoperative lymphoscintigraphy is a prerequisite for characterizing the lymphatic drainage pattern in patients with primary melanoma especially for sites such as the head and neck as well as the trunk before selective SLN dissection [Leong 1999a]. Our studies are in agreement with other studies [Wanebo 1985, Uren 1993, Berman 1992, Thompson 1994]. Therefore, it is mandatory to have preoperative lymphoscintigraphy prior to selective sentinel lymphadenectomy.
The lymphatics of the breast. British Journal of Surgery 1953;46:574-82 Vendrell-Torne E, Setoain-Quinquer J, Domenech-Torne FM. Study of normal mammary lymphatic drainage using radioactive isotopes. Journal of Nuclear Medicine 1972;13(11):801-5 Veronesi U, Paganelli G, Viale G, et al. Sentinel lymph node biopsy and axillary dissection in breast cancer: results in a large series. Journal of the National Cancer Institute 1999;91(4):368-373 Veronesi U, Pagannelli G, Galimberti V, et al. Sentinel node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph nodes.
Atlas of Selective Sentinel Lymphadenectomy for Melanoma, Breast Cancer and Colon Cancer by Jan H. Wong MD (auth.), Stanley P. L. Leong (eds.)