By Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann

ISBN-10: 084123745X

ISBN-13: 9780841237452

Describes innovative ways within the improvement of anticancer brokers for chemotherapy. those new and interdisciplinary techniques are aimed toward the improvement of tumor particular anticancer brokers whereas expanding the efficiency opposed to drug-resistant tumors. the amount contains an outline of latest paradigms for melanoma drug discovery and improvement by way of NCI, new iteration cytotoxic brokers, mechanism established enzyme inhibitors as anticancer brokers, anti-angiogenesis brokers, antitumor vaccines, and tumor activated prodrugs utilizing immunoconjugates of monoclonal antibodies with cytotoxic brokers.

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Fr J OYCE L. edu R ASHA S. gov J. W ILLIAM H ARBOUR Department of Ophthalmology and Visual Sciences Washington University School of Medicine St. edu M ARK H ARLAND Section of Epidemiology and Biostatistics Cancer Research UK Clinical Centre, Leeds Institute of Molecular Medicine, St. uk A DRIAN L. jp D AVID G. H EIDT Department of Surgery University of Michigan Medical Center Ann Arbor, MI USA J OHN . D. uk L ILI H E Molecular Oncology and Pathology H. nl S TEPHEN S. edu PAUL W. S. sg A HMED E.

Gov E RIC J. gov J AY A. D. tw J ANET C. uk C HRISTOPHER A. gov H OLGER N. de L AWRENCE A. de V INATA B. es C HARLES L. edu E DITH M. org R AGNHILD A. no M ICHAEL T. edu C HRYSTAL U. gov D AVID B. au List of Contributors J IADE J. edu G ARY H. edu I RINA A. it S COTT K. de B RITTA M ÄDGE DKFZ Heidelberg Germany B EN O. edu liii liv List of Contributors R OLANDO F. de S OURINDRA N. D. it A SHLEY A. edu L UCIA M ARCOCCI Department of Biochemical Sciences “A. de D EBORAH J. au J OHN L. edu R ENÉE M.

Net D AVID P. ca C HEONG J. gov E RIC J. gov J AY A. D. tw J ANET C. uk C HRISTOPHER A. gov H OLGER N. de L AWRENCE A. de V INATA B. es C HARLES L. edu E DITH M. org R AGNHILD A. no M ICHAEL T. edu C HRYSTAL U. gov D AVID B. au List of Contributors J IADE J. edu G ARY H. edu I RINA A. it S COTT K. de B RITTA M ÄDGE DKFZ Heidelberg Germany B EN O. edu liii liv List of Contributors R OLANDO F. de S OURINDRA N. D. it A SHLEY A. edu L UCIA M ARCOCCI Department of Biochemical Sciences “A. de D EBORAH J.

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Anticancer Agents: Frontiers in Cancer Chemotherapy by Iwao Ojima, Gregory D. Vite, Karl-Heinz Altmann


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